Virginia B Kraus Selected Research

Osteophyte

1/2022	Multivariable Modeling of Biomarker Data From the Phase I Foundation for the National Institutes of Health Osteoarthritis Biomarkers Consortium.
1/2021	A matrix metalloproteinase-generated neoepitope of CRP can identify knee and multi-joint inflammation in osteoarthritis.
10/2020	The combination of an inflammatory peripheral blood gene expression and imaging biomarkers enhance prediction of radiographic progression in knee osteoarthritis.
1/2020	Transgenic conversion of ω-6 to ω-3 polyunsaturated fatty acids via fat-1 reduces the severity of post-traumatic osteoarthritis.
1/2017	Association Between Biochemical Markers of Bone Turnover and Bone Changes on Imaging: Data From the Osteoarthritis Initiative.
9/2014	Alpha C-telopeptide of type I collagen is associated with subchondral bone turnover and predicts progression of joint space narrowing and osteophytes in osteoarthritis.
8/2011	Biomarkers of incident radiographic knee osteoarthritis: do they vary by chronic knee symptoms?
3/2010	First qualification study of serum biomarkers as indicators of total body burden of osteoarthritis.
6/2004	Ascorbic acid increases the severity of spontaneous knee osteoarthritis in a guinea pig model.

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Virginia B Kraus Research Topics

Disease

51	Osteoarthritis 01/2022 - 03/2002
29	Inflammation (Inflammations) 01/2022 - 02/2002
20	Knee Osteoarthritis 01/2022 - 06/2004
17	Pain (Aches) 01/2021 - 08/2005
11	Arthritis (Polyarthritis) 01/2020 - 02/2002
9	Osteophyte 01/2022 - 06/2004
9	Rheumatoid Arthritis 01/2020 - 11/2004
8	Insulin Resistance 01/2022 - 01/2012
8	Obesity 01/2022 - 02/2007
7	Wounds and Injuries (Trauma) 01/2018 - 01/2009
6	Synovitis 01/2022 - 03/2013
5	Cardiovascular Diseases (Cardiovascular Disease) 12/2022 - 02/2007
3	Ankle Fractures 03/2022 - 05/2015
3	Anterior Cruciate Ligament Injuries 01/2020 - 01/2017
3	Knee Injuries (Knee Injury) 04/2018 - 01/2010
3	Hyperalgesia 03/2014 - 04/2009
2	Chronic Disease (Chronic Diseases) 12/2022 - 06/2012
2	Type 2 Diabetes Mellitus (MODY) 01/2022 - 01/2021
2	Weight Loss (Weight Reduction) 01/2021 - 02/2012
2	Prediabetic State (Prediabetes) 01/2020 - 12/2018
2	Hemarthrosis 01/2020 - 05/2017
2	Intra-Articular Fractures 11/2015 - 01/2013
2	Musculoskeletal Diseases (Musculoskeletal Disease) 02/2007 - 12/2006
2	Relapsing Polychondritis 11/2004 - 10/2003
1	Hematoma 03/2022
1	Sarcopenia 01/2022
1	Disease Progression 01/2021
1	Bone Resorption 01/2021
1	Contusions 01/2020
1	Rupture 01/2020
1	Joint Instability (Joint Laxity) 04/2019
1	Tibial Fractures (Fracture, Tibial) 01/2019
1	Bone Fractures (Bone Fracture) 01/2019

Drug/Important Bio-Agent (IBA)

45	Biomarkers (Surrogate Marker)IBA 01/2022 - 02/2002
21	CytokinesIBA 01/2021 - 06/2004
6	C-Reactive ProteinIBA 01/2021 - 02/2007
5	LipidsIBA 01/2022 - 05/2011
5	CollagenIBA 01/2021 - 02/2007
5	AdipokinesIBA 01/2020 - 01/2010
5	Proteins (Proteins, Gene)FDA Link 01/2020 - 10/2006
4	Collagen Type II (Type II Collagen)IBA 01/2022 - 10/2003
4	Interleukin-18 (Interleukin 18)IBA 02/2017 - 02/2011
3	CholesterolIBA 01/2022 - 09/2012
3	Lipoproteins (Lipoprotein)IBA 01/2022 - 02/2017
3	Collagen Type I (Type I Collagen)IBA 01/2022 - 09/2014
3	Matrix Metalloproteinases (MMPs)IBA 01/2021 - 11/2015
3	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2020 - 11/2007
3	EnzymesIBA 01/2020 - 01/2017
3	Insulin (Novolin)FDA Link 01/2020 - 10/2014
3	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 02/2012
3	Interleukin-6 (Interleukin 6)IBA 12/2018 - 03/2014
3	Amino Acids FDA Link 01/2017 - 12/2006
3	LeptinIBA 01/2016 - 10/2009
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2014 - 10/2003
3	Hyaluronic Acid (Hyaluronan)IBA 08/2011 - 01/2005
3	Cartilage Oligomeric Matrix ProteinIBA 08/2011 - 02/2003
3	Ascorbic Acid (Vitamin C)FDA LinkGeneric 09/2005 - 03/2002
2	Pharmaceutical PreparationsIBA 01/2022 - 01/2010
2	Triglycerides (Triacylglycerol)IBA 01/2022 - 09/2012
2	Aggrecans (Aggrecan)IBA 01/2022 - 01/2020
2	ApolipoproteinsIBA 01/2022 - 01/2019
2	collagen type I trimeric cross-linked peptideIBA 01/2022 - 09/2014
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2020 - 11/2015
2	Triamcinolone Acetonide (Azmacort)FDA LinkGeneric 03/2019 - 04/2018
2	Adrenal Cortex Hormones (Corticosteroids)IBA 04/2018 - 02/2017
2	InterleukinsIBA 02/2017 - 10/2014
2	Colchicine FDA LinkGeneric 12/2015 - 04/2015
2	Uric Acid (Urate)IBA 04/2015 - 02/2011
2	Interleukin-1 (Interleukin 1)IBA 06/2014 - 03/2013
2	AdiponectinIBA 10/2012 - 01/2010
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 02/2007 - 08/2005
1	Hemoglobins (Hemoglobin)IBA 12/2022
1	FructosamineIBA 12/2022
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 03/2022
1	Sirolimus (Rapamycin)FDA Link 01/2022
1	LDL Lipoproteins (beta Lipoproteins)IBA 01/2022
1	Branched-Chain Amino AcidsIBA 01/2022
1	HDL LipoproteinsIBA 01/2022
1	Transforming Growth Factors (Transforming Growth Factor)IBA 12/2021
1	Pancreatic Elastase (Elastase)IBA 01/2021
1	Collagen Type III (Type III Collagen)IBA 01/2021
1	catch-relaxing peptide (Mytilus)IBA 01/2021
1	Radioisotopes (Radionuclides)IBA 01/2021
1	Messenger RNA (mRNA)IBA 10/2020
1	Membrane Glycoproteins (Membrane Glycoprotein)IBA 01/2020
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2020
1	Protein Isoforms (Isoforms)IBA 01/2020
1	HLA-DQA1 antigen (HLA DQA1)IBA 01/2020
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2020
1	RNA (Ribonucleic Acid)IBA 01/2020
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2020
1	HLA-DQA2 antigenIBA 01/2020
1	ProteomeIBA 01/2020
1	mesoglycanIBA 01/2019

Therapy/Procedure

8	Therapeutics 04/2015 - 06/2004
2	Intra-Articular Injections 04/2018 - 01/2014
1	Resistance Training 01/2021
1	Transplantation 01/2020
1	Rejuvenation 01/2020
1	Ambulatory Care (Outpatient Care) 04/2019